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Frontline Plus Flea and Tick Treatment for Large Dogs Up to 45 to 88 lbs. 3 Treatments
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Frontline Plus Flea and Tick Treatment for Large Dogs Up to 45 to 88 lbs. 3 Treatments

Original price was: $49.99.Current price is: $34.98.

Keep your dog protected with the number 1 name in flea & tick protection (1), FRONTLINE. FRONTLINE Plus for Dogs is a fast-acting, long-lasting waterproof flea & tick topical that’s proven to kill fleas, flea eggs, flea larvae, chewing lice, and ticks that can transmit Lyme disease. Break the flea life cycle — FRONTLINE Plus for Dogs is specially formulated with fipronil and (S)-methoprene to kill existing adult fleas, flea eggs and flea larvae to guard against further infestations for flea control. Trusted by pet owners for over 20 years (2) — FRONTLINE Plus for Dogs can be used on puppies as young as eight weeks old, weighing 5 pounds or more, and is easy to apply. Applied to a single point on your pet, the flea and tick control treatment covers your dog’s entire body and deposits in the sebaceous glands. These glands act as a reservoir, continuously replenishing the treatment onto your pet, working even if your dog gets wet. Just one dose of FRONTLINE Plus each month protects against fleas & ticks for a full 30 days. FRONTLINE Plus also comes in a formula designed for cats and kittens eight weeks of age and older, 1.5lbs. and over so you can protect the dogs or cats in your house from fleas and ticks with FRONTLINE Brand Products. Appropriately treat all pets in your household monthly to effectively control fleas and ticks and prevent the establishment of new flea infestations. Subscribe and save today to make it easier to keep your dogs or cats protected year-round and make sure you never run out of FRONTLINE Plus. Be sure to visit our brand store and follow us to stay up to date on new FRONTLINE products, features, tips and more. References: (1) BI Marketing Excellence Survey performed by Kynetec, November 2023. (2) 20 years of trust in killing fleas and ticks demonstrated by various studies in the past 20 years including a 2002 Pet Owner Brand Awareness and Attitude Tracking Study performed by Bruno and Ridgway Research Associates and the 2023 BrandSpark© American Trust Study where FRONTLINE Brand Products were voted most trusted for brand for flea & tick prevention.
Is Discontinued By Manufacturer ‏ : ‎ No
Product Dimensions ‏ : ‎ 5.75 x 0.75 x 4.5 inches; 0.64 ounces
Manufacturer recommended age ‏ : ‎ 1 month and up
Item model number ‏ : ‎ 72219
Department ‏ : ‎ Insect Control
Date First Available ‏ : ‎ September 2, 2004
Manufacturer ‏ : ‎ Boehringer Ingelheim Animal Health
ASIN ‏ : ‎ B0002J1FOE
Country of Origin ‏ : ‎ Germany

Keep your dog protected from fleas & ticks all month long with FRONTLINE Plus for Dogs a fast-acting, waterproof flea & tick topical that’s proven to kill fleas, flea eggs, flea larvae, chewing lice, and ticks that can transmit Lyme disease
Break the flea life cycle with FRONTLINE Plus, specially formulated with fipronil and (S)-methoprene to kill existing adult fleas, flea eggs and flea larvae to guard against further infestations for flea control
Trusted by pet owners for over 20 years, FRONTLINE Plus for Dogs can be used on puppies as young as eight weeks old, weighing 5 pounds or more, and is easy to apply with one monthly dose providing protection from fleas & ticks for a full 30 days
FRONTLINE Plus also comes in a formula designed for cats and kittens eight weeks of age and older, 1.5lbs. and over, so you can protect the dogs or cats in your house from fleas and ticks with FRONTLINE Brand Products
Treat all dogs or cats in your household monthly to effectively control fleas and ticks and prevent the establishment of new flea infestations
Subscribe & save today to make it easier to keep your dogs or cats protected year-round and make sure you never run out of FRONTLINE Plus
Subscribe & save today to make it easier to keep your dogs or cats protected year-round and make sure you never run out of FRONTLINE Plus

Frontline Plus Flea and Tick Treatment for Large Dogs Up to 45 to 88 lbs. 3 Treatments
Price: $49.99 - $34.98
(as of Sep 05, 2024 18:30:05 UTC – Details)



Keep your dog protected with the number 1 name in flea & tick protection (1), FRONTLINE. FRONTLINE Plus for Dogs is a fast-acting, long-lasting waterproof flea & tick topical that’s proven to kill fleas, flea eggs, flea larvae, chewing lice, and ticks that can transmit Lyme disease. Break the flea life cycle — FRONTLINE Plus for Dogs is specially formulated with fipronil and (S)-methoprene to kill existing adult fleas, flea eggs and flea larvae to guard against further infestations for flea control. Trusted by pet owners for over 20 years (2) — FRONTLINE Plus for Dogs can be used on puppies as young as eight weeks old, weighing 5 pounds or more, and is easy to apply. Applied to a single point on your pet, the flea and tick control treatment covers your dog’s entire body and deposits in the sebaceous glands. These glands act as a reservoir, continuously replenishing the treatment onto your pet, working even if your dog gets wet. Just one dose of FRONTLINE Plus each month protects against fleas & ticks for a full 30 days. FRONTLINE Plus also comes in a formula designed for cats and kittens eight weeks of age and older, 1.5lbs. and over so you can protect the dogs or cats in your house from fleas and ticks with FRONTLINE Brand Products. Appropriately treat all pets in your household monthly to effectively control fleas and ticks and prevent the establishment of new flea infestations. Subscribe and save today to make it easier to keep your dogs or cats protected year-round and make sure you never run out of FRONTLINE Plus. Be sure to visit our brand store and follow us to stay up to date on new FRONTLINE products, features, tips and more. References: (1) BI Marketing Excellence Survey performed by Kynetec, November 2023. (2) 20 years of trust in killing fleas and ticks demonstrated by various studies in the past 20 years including a 2002 Pet Owner Brand Awareness and Attitude Tracking Study performed by Bruno and Ridgway Research Associates and the 2023 BrandSpark© American Trust Study where FRONTLINE Brand Products were voted most trusted for brand for flea & tick prevention.
Is Discontinued By Manufacturer ‏ : ‎ No
Product Dimensions ‏ : ‎ 5.75 x 0.75 x 4.5 inches; 0.64 ounces
Manufacturer recommended age ‏ : ‎ 1 month and up
Item model number ‏ : ‎ 72219
Department ‏ : ‎ Insect Control
Date First Available ‏ : ‎ September 2, 2004
Manufacturer ‏ : ‎ Boehringer Ingelheim Animal Health
ASIN ‏ : ‎ B0002J1FOE
Country of Origin ‏ : ‎ Germany

Keep your dog protected from fleas & ticks all month long with FRONTLINE Plus for Dogs a fast-acting, waterproof flea & tick topical that’s proven to kill fleas, flea eggs, flea larvae, chewing lice, and ticks that can transmit Lyme disease
Break the flea life cycle with FRONTLINE Plus, specially formulated with fipronil and (S)-methoprene to kill existing adult fleas, flea eggs and flea larvae to guard against further infestations for flea control
Trusted by pet owners for over 20 years, FRONTLINE Plus for Dogs can be used on puppies as young as eight weeks old, weighing 5 pounds or more, and is easy to apply with one monthly dose providing protection from fleas & ticks for a full 30 days
FRONTLINE Plus also comes in a formula designed for cats and kittens eight weeks of age and older, 1.5lbs. and over, so you can protect the dogs or cats in your house from fleas and ticks with FRONTLINE Brand Products
Treat all dogs or cats in your household monthly to effectively control fleas and ticks and prevent the establishment of new flea infestations
Subscribe & save today to make it easier to keep your dogs or cats protected year-round and make sure you never run out of FRONTLINE Plus
Subscribe & save today to make it easier to keep your dogs or cats protected year-round and make sure you never run out of FRONTLINE Plus

Customers say

Customers like the quality and ease of use of the pet pest control. For example, they mention it works as advertised, is easy to apply topically, and doesn’t cause too much of a pain. That said, opinions are mixed on performance, flea resistance, value, and side effects.

AI-generated from the text of customer reviews

10 reviews for Frontline Plus Flea and Tick Treatment for Large Dogs Up to 45 to 88 lbs. 3 Treatments

  1. Amazon Customer

    Did NOT work!!
    Fleas are horrible. Did not work at all.

  2. Jae

    It does the job still!
    I’ve been using Frontline’s quality flea and tick treatment since I first started working in animal rescue and care, and more so when I began having my own pets over the last 8 years. It’s quick and easy to use, safe to use (if used properly) and always effective if you have the dosage correct for the animal. Best of all? Never had flea infestations while using this product… hint, hint to all buyers.

  3. Henny pen caretaker

    Fleas have fled the scene!
    Great value! I am extremely pleased and my dog is egg-static! Stopped her early summer flea confrontation and no issues ever since! My favorite brand and method now!

  4. Peter Suslock

    Your Safest Bet For A Product You Wish You Didn’t Need.
    Allow me to caveat this review by saying out of 700 plus reviews this is the most difficult to write as I despise having to use pesticides on our dogs. That said, we live in Tick and Flea central, surrounded by deep woods and our bulldogs are in every sense of the word family and we do whatever we must to protect them. That said if you’re reading these reviews your dog or dogs are your heart too and using these products is a difficult choice to make, but it’s one we have to make.On that note, it’s my hope the following information has some value for you.Frontline was first put into clinical trials in 1985 shortly after the discovery of it’s active ingredient Fipronil. To it’s credit Frontline has maintained the safest albeit not the most effective treatment for fleas and ticks. However, the more effective products pose a significantly greater risk to your dog.It’s a slippery slope, but in evaluating what’s best for your dog by providing the highest level protection with the lowest risk Frontline and FrontLine Plus are in my opinion your best bet.Most tick and flea products contain Permethrin which may also be listed as Lyclear or Nix as the active ingredient. Permethrin is a lethal neurotoxin that flows through the dogs circulatory system and flushes into every major organ – including the brain where it can do dire damage. Thousands of dogs die every year from Permethrin. Although the FDA has mandated a minimal use not to exceed 750PPM companies continue to ignore the guidline because it’s cheap and effective, and sadly it’s our dogs that pay the price.What makes Permethrin so dangerous is that it can’t distinguish between insects and mammals which of course includes human beings. It’s been known to be lethal to cats since the 1970’s. In fact it’s so deadly to cats that even a slight transfer from dog to cat can result in seizures, brain damage and death. Permethrin is volatile as well – meaning it’s airborne properties pose a threat to all who breath it in – humans included.Frontline on the other hand uses Fipronil. Fipronil is an insecticide.Like any chemical of this nature it can be lethal at too high of a dose. However studies including those from the Department of Environmental Conservation have determined time and time again that as long as the amount of Fipronil is at the correct dose for the weight and size of your dog toxicity is far easier to avoid and the product much safer for your dog. Unlike Premethrin, Fipronil is absorbed into the hair follicles and oil glands only. It is not absorbed into the dogs system nor is it volatile so you and your beloved pets and children can breath easy. The second active ingredient in FrontLine Plus is Methoprene which is a long existing and time proven IGR (insect growth regulator) it’s distributed exactly like Fipronil but only acts on flea and tick eggs and Larvae – this is important because it kills these vermin at the start of a new life cycle. What is more, the diseases that ticks carry now are infinitely more serious than the dreaded Lime disease – which for decades was the only concern.Competitors to Frontline (and some Vets selling other products) claim that fleas and ticks have become resistant to Frontline – However these pests have become resistant to some degree to all pesticides and no independent research exists to confirm this claim. I can assure you I’ve researched this in the greatest depth.The bottom line is this – all of these products pose a risk.The wise choice is to minimize that risk in your effort to protect your best friend from the diseases these vermin carry. Again, these diseases can be infinitely more lethal than the ingredients of the protection. To that end your safest and most effective choice is Frontline or Frontline Plus.In the event your pet has a bad reaction to Frontline products these are the symptoms you would see:* Restlessness* Itching* Vomiting* Difficulty Breathing* LethargyShould these symptoms occur, of course take your pet to your Veterinarian or emergency clinic immediately. It should be a comfort to know that unlike the toxic ingredients in most other flea and tick control products severe reactions to both Fipronil and Methoprene are rare.

  5. Howard Wildermuth

    Doesn’t work
    Waste of money doesn’t work fleas are horrible

  6. Mrs. Will

    Works great!
    This has always worked great for fleas and ticks. But know that it does not repel ticks in any way. They have to bite the dog to kill the tick so you will find dead ticks in your dog.

  7. le bon chemin

    Good!
    I’ve used Frontline for years. It works well. Easy to apply. And I like it better than the oral medicine.

  8. Sierra

    Need more often
    I’ve been putting this on my boys for a few years now but it seems like I need to apply it more often – like once a month. When it is fresh – they still get ticks on them but if they bite they die instantly and I still have to pick the ticks off. It works, but if you’re in a heavily tick’d area, then be prepared to apply regularly. It does create their hair along their back kind of greasy for a few days and I have to keep my kids from petting them, and try to not let the dogs roll around outside with a fresh batch.All in all – it works just fine for the price. Not insanely expensive and not the super highest quality.

  9. Douglas fernandes

    It was very helpful I managed to get control of the continue scratching on her back

  10. Sen-Sen

    It works

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